Colonia del Sacramento lies across the Rio de la Plata from Buenos Aires to the west of Montevideo, and is the main water thoroughfare for visitors from Argentina to access any part of Uruguay. It is a resort city, a port, and the trade centre for agricultural produce. The only Portuguese settlement along the Rio de la Plata, it has stone houses and cobblestoned streets in an historic area reminiscent of old Lisbon with winding streets and colourful houses. The historic quarter, Barrío Historico, on a small peninsula jutting out into the river, was named a UNESCO heritage site in 1995. Sights include Plaza Mayor with several interesting buildings and museums, Puerta del Capo - the restored city gate and drawbridge and thr fortifications of Bastion del Carmen.
Founded as Nova Colonia do Sacramento in 1680 by Manuel de Lobo, it was the focus of struggle between the Spanish, who founded the settlement at Montevideo in response, and the Portuguese over control of the area. In the 17th century it operated as a contraband port, smuggling British goods into the Spanish colonies across the Rio de la Plata. Today .
There are no cruises currently listed for this port of call.